Invention Grant
- Patent Title: ENA nucleic acid pharmaceuticals capable of modifying splicing of mRNA precursors
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Application No.: US14858404Application Date: 2015-09-18
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Publication No.: US09657050B2Publication Date: 2017-05-23
- Inventor: Masafumi Matsuo , Yasuhiro Takeshima , Makoto Koizumi
- Applicant: DAIICHI SANKYO COMPANY, LIMITED , Masafumi Matsuo , Yasuhiro Takeshima , Orphan Disease Treatment Institute Co., Ltd.
- Applicant Address: JP Kobe-shi JP Nishinomiya JP Tokyo JP Tokyo
- Assignee: Matsuo Masafumi,Takeshima Yasuhiro,Daiichi Sankyo Company, Limited,Orphan Disease Treatment Institute Co., Ltd.
- Current Assignee: Matsuo Masafumi,Takeshima Yasuhiro,Daiichi Sankyo Company, Limited,Orphan Disease Treatment Institute Co., Ltd.
- Current Assignee Address: JP Kobe-shi JP Nishinomiya JP Tokyo JP Tokyo
- Agency: Oblon, McClelland, Maier & Neustadt, L.L.P.
- Priority: JP2002-340857 20021125; JP2003-204381 20030731
- Main IPC: C07H21/02
- IPC: C07H21/02 ; C07H21/04 ; C12N15/113 ; A61K38/00 ; A61K48/00
Abstract:
Oligonucleotides having a nucleotide sequence complementary to nucleotide numbers such as 2571-2607, 2578-2592, 2571-2592, 2573-2592, 2578-2596, 2578-2601 or 2575-2592 of the dystrophin cDNA (Gene Bank accession No. NM_004006.1) and therapeutic agents for muscular dystrophy comprising such oligonucleotides.
Public/Granted literature
- US20160002636A1 ENA NUCLEIC ACID PHARMACEUTICALS CAPABLE OF MODIFYING SPLICING OF mRNA PRECURSORS Public/Granted day:2016-01-07
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