- Patent Title: Inhibiting peptides derived from triggering receptor expressed on myeloid cells-1 (TREM-1) TREM-like transcript 1 (TLT-1) for treatment of cardiovascular diseases
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Application No.: US14426562Application Date: 2013-09-09
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Publication No.: US09657081B2Publication Date: 2017-05-23
- Inventor: Sebastien Gibot , Amir Boufenzer , Hafid Ait-Oufella , Marc Derive
- Applicant: INSERM (Institut National de la Sante et de la Recherche Medicale) , UNIVERSITE DE LORRAINE
- Applicant Address: FR Paris FR Nancy
- Assignee: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE),UNIVERSITE DE LORRAINE
- Current Assignee: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE),UNIVERSITE DE LORRAINE
- Current Assignee Address: FR Paris FR Nancy
- Agency: Whitham, Curtis & Cook, P.C.
- International Application: PCT/EP2013/068628 WO 20130909
- International Announcement: WO2014/037565 WO 20140313
- Main IPC: A61K31/04
- IPC: A61K31/04 ; A61P9/00 ; C07K14/705
Abstract:
The present invention relates to a peptide comprising at least 6 consecutive amino acid selected from the amino acid sequence SEQ ID NO: 2 and a function-conservative variant. The invention also relates to a peptide comprising at least 6 consecutive amino acid selected from the amino acid sequence SEQ ID NO: 1 or SEQ ID NO: 2 and a function-conservative variant for use in the treatment of a cardiovascular disease.
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