Invention Grant
- Patent Title: Optimized Fc variants
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Application No.: US14507783Application Date: 2014-10-06
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Publication No.: US09657106B2Publication Date: 2017-05-23
- Inventor: Gregory Lazar , Wei Dang , John Desjarlais , Sher Karki , Omid Vafa , Robert Hayes , Jost Vielmetter
- Applicant: Xencor, Inc.
- Applicant Address: US CA Monrovia
- Assignee: Xencor, Inc.
- Current Assignee: Xencor, Inc.
- Current Assignee Address: US CA Monrovia
- Agency: Morgan, Lewis & Bockius, LLP
- Agent Robin M. Silva; Christina A. MacDougall
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C07K16/28 ; C07K16/32 ; C07K16/30 ; C07K16/18 ; C07K1/00 ; A61K39/00
Abstract:
The present invention relates to Fc variants having decreased affinity for FcγRIIb, methods for their generation, Fc polypeptides comprising optimized Fc variants, and methods for using optimized Fc variants.
Public/Granted literature
- US20160304589A9 OPTIMIZED Fc VARIANTS Public/Granted day:2016-10-20
Information query
