Invention Grant
- Patent Title: Lentiviral vectors containing an MHC class I, MHC class II, or B2 microglobulin upstream promoter sequence
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Application No.: US14287699Application Date: 2014-05-27
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Publication No.: US09657311B2Publication Date: 2017-05-23
- Inventor: Cecile Bauche , Emeline Sarry
- Applicant: THERAVECTYS
- Applicant Address: FR Villejuif
- Assignee: THERAVECTYS
- Current Assignee: THERAVECTYS
- Current Assignee Address: FR Villejuif
- Agency: Whitham, Curtis & Cook, P.C.
- Priority: EP13305738 20130603
- Main IPC: C12N15/86
- IPC: C12N15/86
Abstract:
The present invention relates to the insertion of an MHC class I, MHC Class II, or β2 microglobulin upstream promoter sequence into a lentiviral vector to increase viral titers. The invention encompasses these vectors, methods of making the vectors, and methods of using them, including medicinal uses.
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