Invention Grant
- Patent Title: Methods for modulating thermostability and acid tolerance of microbes
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Application No.: US12558218Application Date: 2009-09-11
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Publication No.: US09657328B2Publication Date: 2017-05-23
- Inventor: Jae-Gu Pan , Mor Dukhova Elena Anatolievna
- Applicant: Jae-Gu Pan , Mor Dukhova Elena Anatolievna
- Applicant Address: KR Yuseong-Gu
- Assignee: Korean Research Institute of Bioscience and Biotechnology
- Current Assignee: Korean Research Institute of Bioscience and Biotechnology
- Current Assignee Address: KR Yuseong-Gu
- Agency: Locke Lord LLP
- Agent Gabriel J. McCool
- Priority: KR10-2008-0126505 20081212
- Main IPC: C12Q1/48
- IPC: C12Q1/48 ; C12N1/36 ; C12N9/10
Abstract:
The present invention relates to a method for modulating thermostability or acid tolerance of a microbe by mutating a nucleic acid molecule encoding a homoserine o-succinyltransferase (MetA) to obtain a nucleic acid molecule encoding a mutant MetA and transforming a microbial cell with the nucleic acid molecule encoding a mutant MetA. The microbe, a bacteria expressing the mutant MetA of the present invention represents a growth rate improved in a vigorous environment such as higher-temperatures and/or lower pH conditions.
Public/Granted literature
- US20100151505A1 METHODS FOR MODULATING THERMOSTABILITY AND ACID TOLERANCE OF MICROBES Public/Granted day:2010-06-17
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