- Patent Title: Propeptide-luciferase fusion proteins and methods of use thereof
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Application No.: US14356864Application Date: 2012-11-07
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Publication No.: US09657329B2Publication Date: 2017-05-23
- Inventor: Sean Burns , David Altshuler , Amedeo Vetere
- Applicant: THE BROAD INSTITUTE, INC. , The General Hospital Corporation , INSTITUTO CARLOS SLIM DE LA SALUD, A.C.
- Applicant Address: US MA Cambridge US MA Boston MX Mexico City
- Assignee: The Broad Institute Inc.,The General Hospital Corporation,Instituto Carlos slim de la Salud, A.C.
- Current Assignee: The Broad Institute Inc.,The General Hospital Corporation,Instituto Carlos slim de la Salud, A.C.
- Current Assignee Address: US MA Cambridge US MA Boston MX Mexico City
- Agency: Vedder Price P.C.
- Agent Thomas J. Kowalski; Deborah L. Lu
- International Application: PCT/US2012/063982 WO 20121107
- International Announcement: WO2013/070796 WO 20130516
- Main IPC: C40B30/06
- IPC: C40B30/06 ; C12Q1/66 ; C12Q1/68 ; G01N33/50 ; C07K14/575 ; C07K14/605 ; C07K14/62 ; C12N9/02 ; G01N33/58
Abstract:
The present invention provides nucleic acid constructs that encode fusion peptides comprising a bioluminescent protein and a precursor of a secreted peptide or protein expressed at the cell surface and high throughput screening assays using same.
Public/Granted literature
- US20140303035A1 PROPEPTIDE-LUCIFERASE FUSION PROTEINS AND METHODS OF USE THEREOF Public/Granted day:2014-10-09
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