A wear member attachment system for an excavation implement can include a retainer with an abutment that engages a forward side of an opening extending through a lip of the excavation implement, the retainer further including a cam. Rotation of the cam displaces the abutment forward relative to a body of the retainer. Another wear member attachment system can include a retainer with a cam and an abutment. Rotation of the cam displaces the abutment outward relative to a body of the retainer. The abutment displacement is in a direction orthogonal to an axis of rotation of the cam.