Invention Grant
- Patent Title: Microelectronic sensor device for detecting label particles
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Application No.: US12518164Application Date: 2007-12-10
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Publication No.: US09658219B2Publication Date: 2017-05-23
- Inventor: Coen Adrianus Verschuren , Dominique Maria Bruls , Albert Hendrik Jan Immink , Femke Karina De Theije , Thea Van Der Wijk , Alexander Marc Van Der Lee , Johannes Joseph Hubertina Barbara Schleipen
- Applicant: Coen Adrianus Verschuren , Dominique Maria Bruls , Albert Hendrik Jan Immink , Femke Karina De Theije , Thea Van Der Wijk , Alexander Marc Van Der Lee , Johannes Joseph Hubertina Barbara Schleipen
- Applicant Address: NL Eindhoven
- Assignee: Koninklijke Philips N.V.
- Current Assignee: Koninklijke Philips N.V.
- Current Assignee Address: NL Eindhoven
- Priority: EP06125907 20061212
- International Application: PCT/IB2007/054979 WO 20071210
- International Announcement: WO2008/072156 WO 20080619
- Main IPC: G01N21/552
- IPC: G01N21/552 ; G01N21/64 ; G01N33/543 ; G01N27/74 ; G01N21/39

Abstract:
A microelectronic sensor device for the detection of target components with label or magnetic particles includes a carrier with a binding surface at which target components can collect and optionally bind to specific capture elements. An input light beam is transmitted into the carrier and totally internally reflected at the binding surface. The amount of light in the output light beam is detected by a light detector. Evanescent light generated during the total internal reflection is affected by target components and/or label particles at the binding surface and will be missing in the output light beam. This is used to determine the amount of target components at the binding surface from the amount of light in the output light beam. A magnetic field generator is optionally used to generate a magnetic field at the binding surface by which magnetic label particles can be manipulated, such as attracted or repelled.
Public/Granted literature
- US20100092996A1 MICROELECTRONIC SENSOR DEVICE FOR DETECTING LABEL PARTICLES Public/Granted day:2010-04-15
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