An embodiment includes a method includes designating a portion of a plurality of processing cores as an input/output (I/O) core and compiling a program source code to produce compiled program source code, including identifying an I/O operation region of the program source code, determining a number of I/O operations for the I/O operation region, and determining a number of system resources and system resource types for the I/O operation region. The method also includes executing the program source code using the plurality of processing cores, including scheduling the I/O operation region of the program source code on the I/O core of the plurality of processing cores.