A system and method for processing large image files using HTML 5 employed by Web Browsers for efficiently process multiple images from the same or different sets of images by one or more client-side users contemporaneously, where the system includes a file server for storing native, processed, or partially processed, image files and meta data associated with the image files, a Web Viewer Cache for dynamic storage of such files and meta data such, a plurality of dedicated Web Servers to perform some or all of the image processing functionality, and a load balancer server dedicated to interfacing with one or more Web Browsers from client-side computers to direct, distribute and manage image retrieval and processing by the dedicated Web Servers regardless of whether a pre-fetch image processing request or a real-time image processing request has been made by the client-side computer users.