A system and method are disclosed to control the power consumption of column drivers in a display system. A video input signal is received which has an active video period and a vertical blanking period between frames. A timing controller transmits a first video frame to a column driver. The timing controller transmits a column driver disable command during a vertical blanking period. Prior to the subsequent active video period, the timing controller transmits a column driver enable command. The timing controller proceeds to transmit a second video frame to the column driver. In one embodiment, the timing controller determines whether to disable and enable the column driver based on a refresh rate, the refresh rate calculated by the timing controller from the video input signal.