A computer-implemented method for using reputation information to evaluate the trustworthiness of files obtained via torrent transactions may include (1) identifying a torrent file that includes metadata for facilitating a torrent transaction for obtaining a target file via a peer-to-peer file-sharing protocol, (2) identifying at least one entity involved in the torrent transaction, (3) obtaining reputation information associated with the entity involved in the torrent transaction, wherein the reputation information identifies a community's opinion on the trustworthiness of the entity, (4) determining, based at least in part on the reputation information associated with the entity involved in the torrent transaction, that the target file represents a potential security risk, and then (5) performing a security action on the target file. Various other methods, systems, and computer-readable media are also disclosed.