Invention Grant
- Patent Title: Crystallisation of thiamine hydrochloride
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Application No.: US15264042Application Date: 2016-09-13
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Publication No.: US09663507B1Publication Date: 2017-05-30
- Inventor: Donal Coveney
- Applicant: Topchem Pharmaceuticals Limited
- Applicant Address: IE
- Assignee: Topchem Pharmaceuticals Limited
- Current Assignee: Topchem Pharmaceuticals Limited
- Current Assignee Address: IE
- Agency: Caesar Rivise, PC
- Main IPC: C07D417/06
- IPC: C07D417/06

Abstract:
A method of producing crystalline pharmaceutical grade Thiamine hydrochloride by crystallization from an isopropanol-water mixture. The method can be tuned to produce either the hemihydrate or monohydrate forms in a simple and easy manner.
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