- Patent Title: Device and method for safe location and marking of a biopsy cavity
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Application No.: US09869282Application Date: 1999-12-23
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Publication No.: US09669113B1Publication Date: 2017-06-06
- Inventor: D. Laksen Sirimanne , Natalie V. Fawzi , Douglas S. Sutton , Gail S. Lebovic , Stanley R. Conston , Peter M. Wilson , Anne B. Morrissey , Mary Elizabeth Bush
- Applicant: D. Laksen Sirimanne , Natalie V. Fawzi , Douglas S. Sutton , Gail S. Lebovic , Stanley R. Conston , Peter M. Wilson , Anne B. Morrissey , Mary Elizabeth Bush
- Applicant Address: US OH Sharonville
- Assignee: DEVICOR MEDICAL PRODUCTS, INC.
- Current Assignee: DEVICOR MEDICAL PRODUCTS, INC.
- Current Assignee Address: US OH Sharonville
- Agency: Arent Fox LLP
- International Application: PCT/US99/30619 WO 19991223
- International Announcement: WO00/38579 WO 20000706
- Main IPC: A61B6/00
- IPC: A61B6/00 ; A61K49/00 ; A61B90/00 ; A61B17/00

Abstract:
Cavity and sentinel lymph node marking devices, marker delivery devices, and methods are disclosed. More particularly, upon insertion into a body, the cavity marking device and method enable one to determine the center, orientation, and periphery of the cavity by radiographic, mammography, echogenic, or other noninvasive imaging techniques. A composition and method are disclosed for locating the sentinel lymph node in a mammalian body to determine if cancerous cells have spread thereto. The composition is preferably a fluid composition consisting of a carrier fluid and some type of contrast agent; alternatively, the contrast agent may itself be a fluid and therefore not need a separate carrier fluid. This composition is capable of (1) deposition in or around a lesion and migration to and accumulation in the associated sentinel node, and (2) remote detection via any number of noninvasive techniques. Also disclosed is a method for remotely detecting the location of a sentinel node by (1) depositing a remotely detectable fluid in or around a lesion for migration to and accumulation in the associated sentinel node and (2) remotely detecting the location of that node with a minimum of trauma and toxicity to the patient. The composition and method may serve to mark a biopsy cavity, as well as mark the sentinel lymph node. The marking methods also may combine any of the features as described with the marking device and delivery device.
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