Invention Grant
- Patent Title: Mitochondrial aldehyde dehyrogenase-2 modulators and methods of use thereof
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Application No.: US14774071Application Date: 2014-03-13
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Publication No.: US09670162B2Publication Date: 2017-06-06
- Inventor: Wenjin Yang , Che-Hong Chen , Daria Mochly-Rosen
- Applicant: The Board of Trustees of the Leland Stanford Junior University
- Applicant Address: US CA Palo Alto
- Assignee: The Board of Trustees of the Leland Stanford Junio
- Current Assignee: The Board of Trustees of the Leland Stanford Junio
- Current Assignee Address: US CA Palo Alto
- Agency: Bozicevic, Field & Francis LLP
- Agent Rudy J. Ng; Paula A. Borden
- International Application: PCT/US2014/025993 WO 20140313
- International Announcement: WO2014/160185 WO 20141002
- Main IPC: C07D213/82
- IPC: C07D213/82 ; A61K31/44 ; C07D213/81 ; C07D401/12 ; C07D405/12 ; C07C311/16 ; C07C311/17 ; C07C311/29 ; C07C311/40 ; C07C317/32 ; C07C233/66 ; C07C233/73 ; C07C233/78 ; C07C233/87 ; C07C235/60 ; C07C237/32 ; C07C235/48 ; C07D213/89 ; C07D317/58 ; C07D403/12 ; C07D413/12 ; C07D417/12
Abstract:
The present disclosure provides compounds of formula (I) that function as modulators of mitochondrial aldehyde dehydrogenase-2 (ALDH2) activity, and methods of preparing these compounds.
Public/Granted literature
- US20160107996A1 Mitochondrial Aldehyde Dehyrogenase-2 Modulators and Methods of Use Thereof Public/Granted day:2016-04-21
Information query
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