Invention Grant
- Patent Title: Protected succinates for enhancing mitochondrial ATP-production
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Application No.: US14433558Application Date: 2013-10-04
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Publication No.: US09670175B2Publication Date: 2017-06-06
- Inventor: Hans Georg Fliri , Rhonan Lee Ford , David Arthur Scowen , Derek Gregory Batcheller , Kari Henrik Johannes Ehinger , Mats Eskil Elmer , Magnus Joakim Hansson , Karl Fredrik Lennart Sjovall
- Applicant: NEUROVIVE PHARMACEUTICALS AB
- Applicant Address: SE Lund
- Assignee: NEUROVIVE PHARMACEUTICALS AB
- Current Assignee: NEUROVIVE PHARMACEUTICALS AB
- Current Assignee Address: SE Lund
- Agency: Foley & Lardner LLP
- Priority: GB1217823.2 20121005; GB1310925.1 20130619
- International Application: PCT/GB2013/052598 WO 20131004
- International Announcement: WO2014/053857 WO 20140410
- Main IPC: A01N43/26
- IPC: A01N43/26 ; A61K31/335 ; C07C69/34 ; C07C69/52 ; C07D317/34 ; C07C69/40 ; C07C69/708 ; C07D323/00 ; C07C235/06

Abstract:
Disclosed herein are mono or di-succinate compounds where one or both of the acid groups in the succinate core are protected in the form of biologically labile moieties, and the use of said compounds to enhance mitochondrial function. The compounds may be of formula (I) wherein R1 is H or an optionally substituted alkyl group or a group of formula (II) and R2 is independently a group according to formula (II) where formula (II) is as defined 10 herein.
Public/Granted literature
- US20150259317A1 PROTECTED SUCCINATES FOR ENHANCING MITOCHONDRIAL ATP-PRODUCTION Public/Granted day:2015-09-17
Information query
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