Invention Grant
- Patent Title: Substituted 6,7-dialkoxy-3-isoquinolinol derivatives as inhibitors of phosphodiesterase 10 (PDE 10A)
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Application No.: US14314930Application Date: 2014-06-25
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Publication No.: US09670181B2Publication Date: 2017-06-06
- Inventor: Bertrand Leblond , Cedric Chauvignac , Thierry Taverne , Eric Beausoleil , Anne-Sophie Casagrande , Laurent Desire , Matthew P. Pando , John E. Donello , Rong Yang
- Applicant: Allergan, Inc.
- Applicant Address: US CA Irvine FR Paris
- Assignee: ALLERGAN, INC.,EXONHIT THERAPEUTICS SA
- Current Assignee: ALLERGAN, INC.,EXONHIT THERAPEUTICS SA
- Current Assignee Address: US CA Irvine FR Paris
- Agent Jonathan Bass
- Main IPC: C07D491/056
- IPC: C07D491/056 ; C07D401/14 ; C07D217/24 ; C07D401/06 ; C07D405/06
Abstract:
The invention relates to compounds of the formula wherein R′, R1 through R7 and Ar are as defined herein. These compounds are useful as inhibitors of phosphodiesterase 10 (PDE10A) which are useful in treating central nervous system diseases such as psychosis and also in treating, for example, obesity, type II diabetes, metabolic syndrome, glucose intolerance, pain and ophthalmic diseases.
Public/Granted literature
- US20140309253A1 SUBSTITUTED 6,7-DIALKOXY-3-ISOQUINOLINOL DERIVATIVES AS INHIBITORS OF PHOSPHODIESTERASE 10 (PDE 10A) Public/Granted day:2014-10-16
Information query
