Invention Grant
- Patent Title: Thiazole-substituted aminoheteroaryls as Spleen Tyrosine Kinase inhibitors
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Application No.: US15105316Application Date: 2014-12-18
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Publication No.: US09670196B2Publication Date: 2017-06-06
- Inventor: Thomas A. Miller , Alessia Petrocchi , Eric T. Romeo , Dilrukshi Vitharana , Solomon D. Kattar , Alan B. Northrup , Michael D. Altman , Neville J. Anthony
- Applicant: Merck Sharp & Dohme Corp.
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Eric A. Meade; Catherine D. Fitch
- International Application: PCT/US2014/071024 WO 20141218
- International Announcement: WO2015/095444 WO 20150625
- Main IPC: C07D417/12
- IPC: C07D417/12 ; C07D417/14 ; C07D413/12 ; C07D471/04 ; C07D491/048 ; C07D495/04 ; A61K31/437 ; A61K31/444 ; A61K31/517 ; A61K31/519
Abstract:
The invention provides certain thiazole-substituted aminoheteroaryl compounds of the Formula (I) (I), or pharmaceutically acceptable salts thereof, wherein ring R1, R2, R3, R4, ring A, and the subscripts n1, n2, and r are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk).
Public/Granted literature
- US20160326156A1 THIAZOLE-SUBSTITUTED AMINOHETEROARYLS AS SPLEEN TYROSINE KINASE INHIBITORS Public/Granted day:2016-11-10
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