Invention Grant
- Patent Title: Class of HDAC inhibitors expands the renal progenitor cells population and improves the rate of recovery from acute kidney injury
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Application No.: US14439855Application Date: 2013-10-31
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Publication No.: US09670236B2Publication Date: 2017-06-06
- Inventor: Neil Hukriede , Billy W. Day , Lee A. McDermott
- Applicant: University of Pittsburgh—Of the Commonwealth System of Higher Education
- Applicant Address: US PA Pittsburgh
- Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
- Current Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
- Current Assignee Address: US PA Pittsburgh
- Agency: The Webb Law Firm
- International Application: PCT/US2013/067728 WO 20131031
- International Announcement: WO2014/071000 WO 20140508
- Main IPC: C07D211/72
- IPC: C07D211/72 ; C07D211/84 ; C07D213/63 ; C07D213/70 ; C07F9/48 ; C07C317/22 ; C07C317/44 ; C07C323/20 ; C07C323/52 ; C07C323/60 ; C07C323/62 ; C07D213/75 ; C07C321/28 ; C07C323/16 ; C07C323/47
Abstract:
Compounds and compositions are provided that inhibit histone deacylase activity and which expand renal progenitor cell populations and improve kidney function in a damaged kidney. Methods of use of the compounds and compositions are provided.
Public/Granted literature
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