- Patent Title: Bright fluorochromes based on multimerization of fluorescent dyes
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Application No.: US14723505Application Date: 2015-05-28
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Publication No.: US09670318B2Publication Date: 2017-06-06
- Inventor: Christian Dose
- Applicant: Miltenyi Biotec GmbH
- Applicant Address: DE Bergisch Gladbach
- Assignee: Miltenyi Biotec GmbH
- Current Assignee: Miltenyi Biotec GmbH
- Current Assignee Address: DE Bergisch Gladbach
- Agent Jaquelin K. Spong
- Main IPC: C08G65/48
- IPC: C08G65/48

Abstract:
The invention is directed to a fluorescent dye according to the general formula I: with C is a core moiety comprising 20 to 200 atoms; S same or different ether residues comprising 1 to 10 carbon atoms; n is an integer ranging from 2 to 500; m is an integer ranging from 0 to 500; x is an integer ranging from 2 to 50; y is an integer ranging from 1 to 50; R same or different residue comprising a reactive group capable of forming a covalent bond with a biomolecule; F same or different fluorophores covalently bound to (S)n. The fluorescent dyes can be conjugated to a biomolecule and used for flow cytometry and/or by fluorescence microscopy.
Public/Granted literature
- US20160347907A1 Bright fluorochromes based on multimerization of fluorescent dyes Public/Granted day:2016-12-01
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