Invention Grant
- Patent Title: Modulation of prekallikrein (PKK) expression
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Application No.: US14915039Application Date: 2014-08-28
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Publication No.: US09670492B2Publication Date: 2017-06-06
- Inventor: Susan M. Freier , Huynh-Hoa Bui
- Applicant: Ionis Pharmaceuticals, Inc.
- Applicant Address: US CA Carlsbad
- Assignee: Ionis Pharmaceuticals, Inc.
- Current Assignee: Ionis Pharmaceuticals, Inc.
- Current Assignee Address: US CA Carlsbad
- Agency: Ionis Pharmaceuticals, Inc. Patent Dept.
- International Application: PCT/US2014/053266 WO 20140828
- International Announcement: WO2015/031679 WO 20150305
- Main IPC: C07H21/02
- IPC: C07H21/02 ; C07H21/04 ; A61K31/70 ; C12N15/113 ; A61K31/7088 ; A61K38/36 ; C12N5/00
Abstract:
Disclosed herein are antisense compounds and methods for decreasing PKK mRNA and protein expression. Such methods, compounds, and compositions are useful to treat, prevent, or ameliorate PKK-associated diseases, disorders, and conditions.
Public/Granted literature
- US20170002359A1 MODULATION OF PREKALLIKREIN (PKK) EXPRESSION Public/Granted day:2017-01-05
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