A method for determining a transverse gradient of a road surface, on which a two-wheeler travels, the two-wheeler having at least one wheel, whose rolling circumference changes as a function of an inclination of the two-wheeler relative to the road surface, an inclination of the two-wheeler relative to the road surface being determined from a variable, which depends on the rolling circumference of the at least one wheel, and the transverse gradient of the road surface being determined from the tilt of the two-wheeler and the inclination relative to the road surface. A corresponding device and a computer program product are also described.