A method for de-ghosting marine seismic trace data is described. A reference seismic trace and a candidate seismic trace are selected from acquired seismic data. The acquired seismic data is gathered using a configuration wherein either a first streamer and a second streamer are disposed at different depths relative to one another and are laterally offset relative to one another, or using a configuration wherein a first source and a second source are disposed at different depths relative to one another and are laterally offset from one another. The reference seismic trace and the candidate seismic trace are processed, e.g., to perform normal moveout correction and/or vertical datum shifting, and the processed reference seismic trace is de-ghosted using the processed, candidate seismic trace.