In accordance with these and other embodiments of the present disclosure, an information handling system may include a processor and a basic input/output system (BIOS) comprising a program of instructions executable by the processor and configured to cause the processor to initialize one or more information handling resources of the information handling system. The BIOS may be further configured to authenticate a signature of a BIOS driver associated with an information handling resource of the information handling system, and, in response to authenticating the signature of the BIOS driver, extracting a vendor public key from the BIOS driver and storing the vendor public key to a key database of the BIOS, wherein the vendor public key may be used by an operating system to authenticate one or more signed operating system drivers signed with a private key corresponding to the vendor public key.