Invention Grant
- Patent Title: PRMT5 inhibitors and uses thereof
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Application No.: US15054193Application Date: 2016-02-26
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Publication No.: US09675614B2Publication Date: 2017-06-13
- Inventor: Kenneth W. Duncan , Richard Chesworth , Paula Ann Boriack-Sjodin , Michael John Munchhof , Lei Jin
- Applicant: Epizyme, Inc.
- Applicant Address: US MA Cambridge
- Assignee: Epizyme, Inc.
- Current Assignee: Epizyme, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Wolf, Greenfield & Sacks, P.C.
- Main IPC: A61K31/506
- IPC: A61K31/506 ; C07D401/14 ; C07D217/12 ; C07D401/12 ; C07D405/12 ; C07D217/04 ; C07D405/14 ; C07D413/12 ; C12N9/10
Abstract:
Described herein are compounds of Formula (I), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting PRMT5 activity. Methods of using the compounds for treating PRMT5-mediated disorders are also described.
Public/Granted literature
- US20170027935A1 PRMT5 INHIBITORS AND USES THEREOF Public/Granted day:2017-02-02
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