A multi-layer biaxially oriented high density polyethylene (OHDPE) film with a novel formulation which exhibits superior heat seal properties is disclosed. This improved formulation comprises a blend of a single grade of high density polyethylene (HDPE) or several grades of high density polyethylene (HDPE) with a nucleating agent (NA) used in the core layer to achieve a lower sealing initiation temperature, higher heat seal strength and broader sealing temperature range HDPE-based film that still exhibits typical properties of OHDPE films and a lower haze than conventional OHDPE films. The multi-layer BOPP film has additional layers such as a third polyolefin resin-containing layer, a metal layer, or combinations thereof.