Disclosed herein are computer devices, systems, and methods for enabling persistent data connections with a vehicle and low-latency vehicle commands. A driver can use an app installed on a mobile device to send commands to a vehicle's DCM, which can execute such commands on one or more vehicle systems, such as remote ignition and door lock systems. Upon app initialization, a wakeup command can be sent to the DCM through one or more intermediary servers to establish a persistent data connection between a data center server and the DCM. Then, when the driver issues a command from the app, the command can be communicated between the data center server and the DCM directly over the persistent data connection, with lower latency. After a predetermined timeout period in which the driver has not used the mobile app, the persistent data connection can be terminated.