Invention Grant
- Patent Title: Aza-epoxy-guaiane derivatives and treatment of cancer
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Application No.: US15116887Application Date: 2015-02-05
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Publication No.: US09676788B2Publication Date: 2017-06-13
- Inventor: William J. Chain , John A. Beutler , David Fash , William D. Figg , Zhenwu Li , Cody John Peer , Joe William Ramos , Florian J. Sulzmaier
- Applicant: The United States of America, as represented by the Secretary, Department of Health and Human Services , University of Hawaii
- Applicant Address: US DC Washington US HI Honolulu
- Assignee: The United States of America, as represented by the Secretary of Health and Human Services,University of Hawaii
- Current Assignee: The United States of America, as represented by the Secretary of Health and Human Services,University of Hawaii
- Current Assignee Address: US DC Washington US HI Honolulu
- Agency: Leydig, Voit & Mayer, Ltd.
- International Application: PCT/US2015/014601 WO 20150205
- International Announcement: WO2015/120140 WO 20150813
- Main IPC: C07D493/08
- IPC: C07D493/08 ; A61K9/00 ; A61K45/06 ; A61K31/352

Abstract:
Disclosed is a compound of formula (I) or formula (II): (Formulas should be inserted here) wherein R1-R6 are as defined herein. Also disclosed are a pharmaceutical composition comprising such a compound and a method of treating or preventing cancer in a mammal in need thereof, comprising administering to the mammal a compound of formula (I) or formula (II).
Public/Granted literature
- US20160347764A1 AZA-EPOXY-GUAIANE DERIVATIVES AND TREATMENT OF CANCER Public/Granted day:2016-12-01
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