- Patent Title: Testosterone derivatives with a carboxyalkyl substitution in position 3 and use thereof for the production of labelled steroids for determining the concentration of testosterone in a biological sample
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Application No.: US14649355Application Date: 2013-12-12
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Publication No.: US09676811B2Publication Date: 2017-06-13
- Inventor: Perrine Cosin , Yuping Guo
- Applicant: BIOMERIEUX
- Applicant Address: FR Marcy l'Etoile
- Assignee: BIOMERIEX
- Current Assignee: BIOMERIEX
- Current Assignee Address: FR Marcy l'Etoile
- Agency: Oliff PLC
- Priority: FR1261982 20121213
- International Application: PCT/FR2013/053040 WO 20131212
- International Announcement: WO2014/091158 WO 20140619
- Main IPC: G01N33/74
- IPC: G01N33/74 ; C07J41/00 ; C07J43/00 ; C07J1/00 ; C07J51/00
Abstract:
A testosterone derivative of formula (I): where n is an integer in a range of from 1 to 10, and Y represents an activated or ready-to-be-activated group allowing formation of an amide bond with a primary amine of a molecule. Conjugates including the testosterone derivatives and a marker, methods for determining the concentration of testosterone in a biological sample, and methods for preparing the testosterone derivatives are also provided.
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