Disclosed are a multi-domain liquid crystal display panel comprising an upper substrate and a lower substrate, wherein at least one of the substrates includes a glass substrate, a conventional alignment layer coated on the surface of the glass substrate, and a polymer alignment layer having a different alignment direction from that of the conventional alignment layer and a method for preparing the same. In the present invention, a smectic/cholesteric liquid crystal polymer is formed from the mixture of liquid crystal polymerizable monomers having smectic phase (Sm)-cholesteric phase (N*) transition, and multiple liquid crystal alignments in a single pixel are formed by adjusting the polymerization temperature, the thickness of the polymer layer, and the amount of the smectic liquid crystal polymerizable monomer, thereby realizing a multi-domain display by the subsequent masking treatment and ultraviolet irradiation. The method for preparing the same is simple, novel, low-cost, and easy to achieve.