A Light-Emitting Diode (LED) driving circuit and a control system includes: a driving control circuit and a constant current channel group circuit, wherein the driving control circuit includes: a logic control circuit and a clock delay circuit; the logic control circuit is connected with the constant current channel group circuit, and is configured to control the ordered switching-on or switching-off of the constant current channel group circuit by virtue of a data control signal; and the clock delay circuit is connected with the logic control circuit, configured to acquire a timing control signal synchronous with the data control signal and output the timing control signal and integrated in the LED driving circuit.