Invention Grant
- Patent Title: Mutant polypeptides and uses thereof
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Application No.: US14833206Application Date: 2015-08-24
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Publication No.: US09683227B2Publication Date: 2017-06-20
- Inventor: Eric Althoff , Nadia Kadi , Mihai Luchian Azoitei , Yih-En A Ban , Daniela Grabs-Röthlisberger , Alexander Pisarchik , Alexandre Zanghellini , Adriana L. Botes
- Applicant: INVISTA North America SA.R.L.
- Applicant Address: US DE Wilmington
- Assignee: INVISTA NORTH AMERICA S.A.R.L.
- Current Assignee: INVISTA NORTH AMERICA S.A.R.L.
- Current Assignee Address: US DE Wilmington
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, LLP
- Agent Carla A. Mouta-Bellum
- Main IPC: C12N9/88
- IPC: C12N9/88 ; A61K38/00 ; C12P5/00 ; C12P5/02 ; C07C11/167 ; C07C11/18 ; C07C11/21 ; C07K16/40 ; C08F36/06 ; C08F36/08 ; C08F36/22 ; G01N33/573 ; C08F136/06 ; C08F136/08
Abstract:
The present disclosure provides novel polypeptides with 3-buten-2-ol dehydratase activity, polypeptides with catalytic activity in the conversion of 3-methyl-3-buten-2-ol to isoprene, and crystal structure data for one of such polypeptides. Methods of making and using the polypeptides and their related crystal structure data are also provided.
Public/Granted literature
- US20160304852A1 MUTANT POLYPEPTIDES AND USES THEREOF Public/Granted day:2016-10-20
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