Invention Grant
- Patent Title: Aptamer-RNAi therapeutic compositions
-
Application No.: US14862065Application Date: 2015-09-22
-
Publication No.: US09683239B2Publication Date: 2017-06-20
- Inventor: Cong-Qiu Chu
- Applicant: OREGON HEALTH & SCIENCE UNIVERSITY , THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS
- Applicant Address: US OR Portland
- Assignee: OREGON HEALTH & SCIENCE UNIVERSITY
- Current Assignee: OREGON HEALTH & SCIENCE UNIVERSITY
- Current Assignee Address: US OR Portland
- Agent Jeffrey M. Jackson
- Main IPC: A61K9/00
- IPC: A61K9/00 ; C12N15/115 ; A61K31/7088 ; C12N15/113
Abstract:
A recombinant nucleic acid comprising an aptamer that binds CD4 and an RNAi sequence that silences the expression of RORγ2 is described herein. Pharmaceutical compositions comprising the recombinant nucleic acid, particularly topical compositions are also described. Methods of treating inflammatory disease using the pharmaceutical composition are also described.
Public/Granted literature
- US09926565B2 Aptamer-RNAi therapeutic compositions Public/Granted day:2018-03-27
Information query
