Invention Grant
- Patent Title: Infectious hepatitis C viruses of genotype 3A and 4A and uses thereof
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Application No.: US14514023Application Date: 2014-10-14
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Publication No.: US09683269B2Publication Date: 2017-06-20
- Inventor: Judith M. Gottwein , Troels Kasper Hoyer Scheel , Robert Purcell , Jens Bukh
- Applicant: Hvidovre Hospital , The United States of America, as Represented by the Secretary, Department of Health and Human Services
- Applicant Address: DK Hvidovre US DC Washington
- Assignee: Hvidovre Hospital,The United States of America, As Represented by the Secretary, Department of Health and Human Services
- Current Assignee: Hvidovre Hospital,The United States of America, As Represented by the Secretary, Department of Health and Human Services
- Current Assignee Address: DK Hvidovre US DC Washington
- Agency: Thompson Copburn, LLP
- Agent Charles P. Romano
- Priority: DK200970143 20091002
- Main IPC: C12N7/00
- IPC: C12N7/00 ; C12Q1/70 ; C12N15/86 ; G01N33/50
Abstract:
The present invention relates to molecular approaches to the production of nucleic acid sequences, which comprises the genome of infectious hepatitis C virus. In particular, the invention provides nucleic acid sequences which comprise the genomes of infectious hepatitis C viruses of either genotype 3a (strain S52) or genotype 4a (strain ED43). The invention therefore relates to the use of the nucleic acid sequences and polypeptides encoded by all or part of the sequences in the development of vaccines and diagnostic assays for HCV and in the development of screening assays for the identification of antiviral agents for HCV. The invention therefore also relates to the use of viral particles derived from laboratory animals infected with S52 and ED43 viruses.
Public/Granted literature
- US20150105290A1 Infectious Hepatitis C Viruses of Genotype 3A and 4A and Uses Thereof Public/Granted day:2015-04-16
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