Invention Grant
- Patent Title: Metal bisphosphonate nanoparticles for anti-cancer therapy and imaging and for treating bone disorders
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Application No.: US14131575Application Date: 2012-07-09
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Publication No.: US09693957B2Publication Date: 2017-07-04
- Inventor: Wenbin Lin , Demin Liu , Joseph Della Rocca , Stephanie A. Kramer , Christopher Y. Poon
- Applicant: Wenbin Lin , Demin Liu , Joseph Della Rocca , Stephanie A. Kramer , Christopher Y. Poon
- Applicant Address: US NC Chapel Hill
- Assignee: The University of North Carolina at Chapel Hill
- Current Assignee: The University of North Carolina at Chapel Hill
- Current Assignee Address: US NC Chapel Hill
- Agency: Jenkins, Wilson, Taylor & Hunt, P.A.
- International Application: PCT/US2012/045954 WO 20120709
- International Announcement: WO2013/009701 WO 20130117
- Main IPC: A61K51/00
- IPC: A61K51/00 ; A61M36/14 ; A61K9/127 ; A61K9/14 ; A61K9/00 ; A61K9/51 ; A61K47/48 ; A61K31/663 ; A61K31/675 ; A61K49/00 ; A61K51/12
Abstract:
Metal-bisphosphonate nanoparticles are disclosed. Also disclosed are pharmaceutical compositions including the metal-bisphosphonate nanoparticles, methods of preparing the metal-bisphosphonate nanoparticles and materials comprising the nanoparticles, and methods of using the compositions to treat cancer or bone-related disorders (e.g., bone-resorption-related diseases, osteoporosis, Paget's disease, and bone metastases) and as imaging agents.
Public/Granted literature
- US20140234210A1 METAL BISPHOSPHONATE NANOPARTICLES FOR ANTI-CANCER THERAPY AND IMAGING AND FOR TREATING BONE DISORDERS Public/Granted day:2014-08-21
Information query
