Invention Grant
- Patent Title: Oral complex composition comprising pseudoephedrine and levocetirizine
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Application No.: US13576338Application Date: 2011-01-18
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Publication No.: US09694007B2Publication Date: 2017-07-04
- Inventor: Jong Soo Woo , Jae Hyun Park , Yong Il Kim , Young Jun Na , Min Jung Kim , Yun Ah Lee
- Applicant: Jong Soo Woo , Jae Hyun Park , Yong Il Kim , Young Jun Na , Min Jung Kim , Yun Ah Lee
- Applicant Address: KR Hwaseong-si
- Assignee: HANMI SCIENCE CO., LTD.
- Current Assignee: HANMI SCIENCE CO., LTD.
- Current Assignee Address: KR Hwaseong-si
- Agency: Sughrue Mion, PLLC
- Priority: KR10-2010-0009314 20100201
- International Application: PCT/KR2011/000367 WO 20110118
- International Announcement: WO2011/093612 WO 20110804
- Main IPC: A61K9/28
- IPC: A61K9/28 ; A61K31/495 ; A61K9/24 ; A61K31/137

Abstract:
An oral complex composition which comprises (i) a core comprising a swellable hydrogel-forming agent and pseudoephedrine, or a pharmaceutically acceptable salt thereof; (ii) a first coating layer encasing the core which comprises a water-soluble substance; and (iii) a second coating layer deposited on the first coating layer which comprises levocetirizine or a pharmaceutically acceptable salt thereof together with polyvinylalcohol, povidone, polyvinylalcohol-polyethyleneglycol graft copolymer or a mixture thereof, has an improved levocetirizine releasing rate and does not show a delayed release behavior even after a long storage period. Accordingly, the inventive oral complex composition is useful for treating perennial or seasonal allergic diseases including nasal obstruction, sneezing, and rhinorrhea.
Public/Granted literature
- US20120301548A1 ORAL COMPLEX COMPOSITION COMPRISING PSEUDOEPHEDRINE AND LEVOCETIRIZINE Public/Granted day:2012-11-29
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