Stabilized compositions of proteins having a free thiol moiety

Invention Grant

US09694057B2 Stabilized compositions of proteins having a free thiol moiety 有权

Patent Title: Stabilized compositions of proteins having a free thiol moiety
Application No.: US14743427

Application Date: 2015-06-18
Publication No.: US09694057B2

Publication Date: 2017-07-04
Inventor: Gaozhong Zhu , Vinh Nguyen , Kris Lowe , Zahra Shahrokh
Applicant: SHIRE HUMAN GENETIC THERAPIES, INC.
Applicant Address: US MA Lexington
Assignee: SHIRE HUMA GENETIC THERAPIES, INC.
Current Assignee: SHIRE HUMA GENETIC THERAPIES, INC.
Current Assignee Address: US MA Lexington
Agency: Troutman Sanders LLP
Main IPC: C12N9/00
IPC: C12N9/00 ; A61K38/43 ; A61K38/47 ; A61K9/00 ; A61K9/19 ; A61K31/7012 ; A61K38/18 ; A61K47/26 ; A61K47/20 ; A61K47/34 ; B65B3/00 ; B65B31/04

Abstract:

Compositions of proteins having free thiols, and methods of making and using such compositions, are described.

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IPC分类:

C	化学；冶金
C12	生物化学；啤酒；烈性酒；果汁酒；醋；微生物学；酶学；突变或遗传工程
C12N	微生物或酶；其组合物；繁殖、保藏或维持微生物；变异或遗传工程；培养基（微生物学的试验介质入C12Q1/00）。
C12N9/00	酶，如连接酶（6.）；酶原；其组合物（用于清洁牙齿的含酶的制剂入A61K8/66、A61Q11/00；含酶或酶原的医药制剂入A61K38/43；含酶去污剂组合物入C11D）；制备、活化、抑制、分离或纯化酶的方法