Invention Grant
- Patent Title: Peptide vaccines based on the EGFRvIII sequence for the treatment of tumors
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Application No.: US14417752Application Date: 2013-08-02
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Publication No.: US09694060B2Publication Date: 2017-07-04
- Inventor: Albert J. Wong
- Applicant: The Board of Trustees of the Leland Stanford Junior University
- Applicant Address: US CA Stanford
- Assignee: The Board of Trustees of the Leland Stanford Junior University
- Current Assignee: The Board of Trustees of the Leland Stanford Junior University
- Current Assignee Address: US CA Stanford
- Agency: Pepper Hamilton LLP
- International Application: PCT/US2013/053521 WO 20130802
- International Announcement: WO2014/022835 WO 20140206
- Main IPC: A61K47/48
- IPC: A61K47/48 ; A61K39/00 ; C07K7/08
Abstract:
Peptides and vaccine compositions comprising peptides based upon EGFRvIII and lacking a glycine at the splice junction are disclosed. The vaccines can induce immune responses against EGFRvIII. Methods of inhibiting formation or growth of EGFvIII tumors, methods of inducing regression of EGFvIII tumors, methods of immunizing against EGFvIII tumors and methods of treating a subjects who have EGFvIII tumors are disclosed.
Public/Granted literature
- US20150216956A1 Peptide Vaccines Based On The EGFRvIII Sequence For The Treatment Of Tumors Public/Granted day:2015-08-06
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