Invention Grant
- Patent Title: Clostridium difficile toxin-based vaccine
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Application No.: US14363387Application Date: 2012-12-07
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Publication No.: US09694063B2Publication Date: 2017-07-04
- Inventor: Maria Scarselli , Mariagrazia Pizza , Rosanna Leuzzi , Maria Arico , Manuele Martinelli , Gillian Douce
- Applicant: GlaxoSmithKline Biologicals SA
- Applicant Address: BE Rixensart
- Assignee: GLAXOSMITHKLINE BIOLOGICALS SA
- Current Assignee: GLAXOSMITHKLINE BIOLOGICALS SA
- Current Assignee Address: BE Rixensart
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: GB1121149.7 20111208; GB1217321.7 20120927
- International Application: PCT/IB2012/002955 WO 20121207
- International Announcement: WO2013/084071 WO 20130613
- Main IPC: A61K39/08
- IPC: A61K39/08 ; C07K14/33 ; A61K39/00
Abstract:
The present invention relates to recombinant fragments of C. difficile TcdA and TcdB that may be used in the development of vaccines against C. difficile associated disease. More particularly it relates to combinations comprising a ToxB-GT antigen and a TcdA antigen or a ToxA-GT antigen and a TcdB antigen.
Public/Granted literature
- US20150132333A1 CLOSTRIDIUM DIFFICILE TOXIN-BASED VACCINE Public/Granted day:2015-05-14
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