Invention Grant
- Patent Title: Monovalent H5 vaccine
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Application No.: US15107074Application Date: 2014-12-12
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Publication No.: US09694067B2Publication Date: 2017-07-04
- Inventor: Fang He , Hwei-Sing Jimmy Kwang , Prabakaran Mookkan
- Applicant: TEMASEK LIFE SCIENCES LABORATORY LIMITED
- Applicant Address: SG Singapore
- Assignee: TEMASEK LIFE SCIENCES LABORATORY LIMITED
- Current Assignee: TEMASEK LIFE SCIENCES LABORATORY LIMITED
- Current Assignee Address: SG Singapore
- Agency: Rothwell, Figg, Ernst & Manbeck, P.C.
- International Application: PCT/SG2014/000594 WO 20141212
- International Announcement: WO2015/099609 WO 20150702
- Main IPC: A61K39/145
- IPC: A61K39/145 ; C12N7/00 ; A61K39/12 ; C07K14/005 ; A61K39/00
Abstract:
The present invention relates to a monovalent H5N1 vaccine. More specifically, the present invention relates to the development of a monovalent H5 vaccine strain using hemagglutinin (HA) engineering to elicit cross-clade protection. The present invention also relates to an epitope-chimeric H5 and to a reverse genetics (RG) influenza virus expressing the epitope-chimeric H5.
Public/Granted literature
- US20170000877A1 MONOVALENT H5 VACCINE Public/Granted day:2017-01-05
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