Invention Grant
- Patent Title: Solid forms comprising 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione and a coformer, compositions and methods of use thereof
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Application No.: US14780289Application Date: 2014-03-25
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Publication No.: US09695146B2Publication Date: 2017-07-04
- Inventor: G. Patrick Stahly , David Jonaitis , Ho-Wah Hui , Kevin J. Klopfer
- Applicant: CELGENE CORPORATION
- Applicant Address: US NJ Summit
- Assignee: Celgene Corporation
- Current Assignee: Celgene Corporation
- Current Assignee Address: US NJ Summit
- Agency: Jones Day
- International Application: PCT/US2014/031694 WO 20140325
- International Announcement: WO2014/160690 WO 20141002
- Main IPC: C07D401/04
- IPC: C07D401/04 ; A61K31/454 ; C07C55/08 ; C07C65/03 ; C07C65/21 ; C07C69/88 ; C07C305/04 ; C07C307/02 ; C07D275/06 ; C07D309/40 ; C07H3/02
Abstract:
Provided herein are solid forms comprising (a) 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione and (b) a coformer. Pharmaceutical compositions comprising the solid forms (e.g., cocrystals) and methods for treating, preventing and managing various disorders are also disclosed.
Public/Granted literature
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