Invention Grant
- Patent Title: 1,2,6-substituted benzimidazoles as flap modulators
-
Application No.: US14777492Application Date: 2014-03-13
-
Publication No.: US09695149B2Publication Date: 2017-07-04
- Inventor: Wenying Chai , Curt A. Dvorak , Wendy Eccles , James P. Edwards , Steven D. Goldberg , Paul J. Krawczuk , Alec D. Lebsack , Jing Liu , Daniel J. Pippel , Zachary S. Sales , Virginia M. Tanis , Mark S. Tichenor , John J. M. Wiener
- Applicant: JANSSEN PHARMACEUTICA NV
- Applicant Address: BE Beerse
- Assignee: JANSSEN PHARMACEUTICA NV
- Current Assignee: JANSSEN PHARMACEUTICA NV
- Current Assignee Address: BE Beerse
- International Application: PCT/US2014/025609 WO 20140313
- International Announcement: WO2014/151380 WO 20140925
- Main IPC: C07D401/12
- IPC: C07D401/12 ; C07D401/14 ; C07D403/12 ; C07D403/14 ; A61K31/4184 ; A61K31/4439 ; A61K31/454 ; A61K31/4545 ; A61K31/506
Abstract:
The present invention relates to compounds of Formula (I), and solvates, hydrates, and pharmaceutically acceptable salts thereof, wherein X1, X1′, X1″, R1, R2 and R3 are as defined herein, useful as FLAP modulators. The invention also relates to pharmaceutical compositions comprising compounds of Formula (I). Methods of making and using the compounds of Formula (I) are also within the scope of the invention.
Public/Granted literature
- US20160039790A1 1,2,6-SUBSTITUTED BENZIMIDAZOLES AS FLAP MODULATORS Public/Granted day:2016-02-11
Information query
