Invention Grant
- Patent Title: Methods useful in the synthesis of halichondrin B analogs
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Application No.: US15059965Application Date: 2016-03-03
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Publication No.: US09695188B2Publication Date: 2017-07-04
- Inventor: Yongbo Hu , Huiming Zhang , Hiroyuki Chiba , Yuki Komatsu , Bryan M. Lewis
- Applicant: Eisai R&D Management Co., Ltd.
- Applicant Address: JP Tokyo
- Assignee: EISAI R&D MANAGEMENT CO., LTD.
- Current Assignee: EISAI R&D MANAGEMENT CO., LTD.
- Current Assignee Address: JP Tokyo
- Agency: Clark & Elbing LLP
- Main IPC: C07D321/00
- IPC: C07D321/00 ; C07D493/22
Abstract:
In general, the present invention features improved methods useful for the synthesis of analogs of halichondrin B, such as eribulin and pharmaceutically acceptable salts thereof (e.g., eribulin mesylate).
Public/Granted literature
- US20160176895A1 METHODS USEFUL IN THE SYNTHESIS OF HALICHONDRIN B ANALOGS Public/Granted day:2016-06-23
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