Invention Grant
- Patent Title: Methods of producing testosteronan polymers using testosteronan synthase
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Application No.: US13981886Application Date: 2012-01-31
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Publication No.: US09695427B2Publication Date: 2017-07-04
- Inventor: Paul L. DeAngelis , Nigel J. Otto
- Applicant: Paul L. DeAngelis , Nigel J. Otto
- Applicant Address: US OK Norman
- Assignee: The Board of Regents of the University of Oklahoma
- Current Assignee: The Board of Regents of the University of Oklahoma
- Current Assignee Address: US OK Norman
- Agency: Dunlap Codding, P.C.
- International Application: PCT/US2012/023351 WO 20120131
- International Announcement: WO2012/106353 WO 20120809
- Main IPC: C12P19/04
- IPC: C12P19/04 ; C12P19/26 ; C08B37/00 ; C12N15/52 ; C12N9/10
Abstract:
Testosteronan, a heparosan analog having the structure [-4-D-GlcUA-α1,4-D-GlcNAc-α1-]n, is produced by testosteronan synthase, a single protein that is a dual-action catalyst that utilizes UDP-GlcUA and UDP-GlcNAc to synthesize a polysaccharide having the structure [-4-D-GlcUA-α1,4-D-GlcNAc-α1-]n.
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