A subsea chemical injection system has a subsea structure, a manifold connected by jumper to the subsea structure, a coiled tubing, a disconnect mechanism affixed to the coiled tubing, and a hose extending from the disconnect mechanism to the manifold such that the chemical flowing through the coil tubing can selectively flow through the disconnect mechanism and through the hose to the subsea structure. The disconnect mechanism is adapted to selectively release from the hose. The disconnect mechanism has a connector affixed thereto. A hydraulic fluid supply is connected to the connector so as to selectively release the connector from the hose. Control lines can extend from a surface location to a control module and the disconnect mechanism for selectively delivering for receiving signals from the subsea structure.