A system and method of using motion or spatial identification technology with a mobile RFID reader to detect whether an RFID tag is part of a forklift load or other ambulatory space such as a shopping cart receptacle, includes determining whether a tag is within a defined space and/or whether a tag is in motion relative to a mobile RFID reader. The system and method determines whether a particular RFID tag is part of a forklift load/space, has been added to or removed, is an extraneous tag, etc.