A wireless device security system for preventing the unauthorized reading of wireless devices by a reader. The wireless device security system generally includes a device holder that is adapted to receive a wireless device for storage, access and removal. The device holder includes an interference tag that interferes with the wireless communications between the wireless device and a reader when the wireless device is positioned at least partially within the device holder. The device holder preferably includes a layer of shielding material adjacent to or near the wireless device during storage to further prevent unauthorized wireless communications with a reader.