Invention Grant
- Patent Title: Use of 1H-indazole-3-carboxamide compounds as glycogen synthase kinase 3 beta inhibitors
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Application No.: US14825261Application Date: 2015-08-13
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Publication No.: US09700551B2Publication Date: 2017-07-11
- Inventor: Maria Alessandra Alisi , Nicola Cazzolla , Barbara Garofalo , Guido Furlotti , Gabriele Magaro' , Rosella Ombrato , Francesca Mancini
- Applicant: AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A.
- Applicant Address: IT Rome
- Assignee: AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A.
- Current Assignee: AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A.
- Current Assignee Address: IT Rome
- Agency: Oblon, McClelland, Maier & Neustadt, L.L.P.
- Priority: EP12156298 20120221
- Main IPC: A61K31/454
- IPC: A61K31/454 ; A61K31/4545 ; A61K31/5377 ; C07D401/14 ; C07D405/14 ; C07D413/14 ; C07D401/12 ; C07D417/14
Abstract:
The present invention relates to the new use of 1H-indazole-3-carboxamide compounds as glycogen synthase kinase 3 beta (GSK-3β) inhibitors and to their use in the treatment of GSK-3β-related disorders such as, for example, (i) insulin-resistance disorders; (ii) neurodegenerative diseases; (iii) mood disorders; (iv) schizophrenic disorders; (v) cancerous disorders; (vi) inflammation, (vii) substance abuse disorders; and (viii) epilepsies.
Public/Granted literature
- US20160045485A1 NEW USE OF 1H-INDAZOLE-3-CARBOXAMIDE COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 BETA INHIBITORS Public/Granted day:2016-02-18
Information query
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