Invention Grant
- Patent Title: Pharmaceutical combinations of a CDK4/6 inhibitor and a B-RAF inhibitor
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Application No.: US14414998Application Date: 2013-07-25
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Publication No.: US09700557B2Publication Date: 2017-07-11
- Inventor: Giordano Caponigro , Darrin Stuart , Sunkyu Kim , Alice Loo , Scott Delach
- Applicant: NOVARTIS AG
- Applicant Address: CH Basel
- Assignee: NOVARTIS AG
- Current Assignee: NOVARTIS AG
- Current Assignee Address: CH Basel
- Agency: Lathrop & Gage LLP
- Agent Brian C. Trinque
- International Application: PCT/US2013/051990 WO 20130725
- International Announcement: WO2014/018725 WO 20140130
- Main IPC: A61K31/519
- IPC: A61K31/519 ; A61K31/4184 ; A61K31/506
Abstract:
A pharmaceutical combination comprising (a) CDK4/6 inhibitor (b) a B-Raf inhibitor, and optionally (c) a MEK 1/2 inhibitor; combined preparations and pharmaceutical compositions thereof; the uses of such combination in the treatment of proliferative diseases; and methods of treating a subject suffering from a proliferative disease comprising administering a therapeutically effective amount of such combination.
Public/Granted literature
- US20150164897A1 Pharmaceutical Combinations of a CDK4/6 Inhibitor and a B-RAF Inhibitor Public/Granted day:2015-06-18
Information query
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