Invention Grant
- Patent Title: Difluorolactam compositions for EP4-mediated osteo related diseases and conditions
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Application No.: US15226295Application Date: 2016-08-02
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Publication No.: US09701630B2Publication Date: 2017-07-11
- Inventor: Stephen Douglas Barrett , Fred Lawrence Ciske , Joseph Michael Colombo , Gregory William Endres , Bradlee David Germain , Andriy Kornilov , James Bernard Kramer , Adam Uzieblo , Thomas Allen Owen , James Paul O'Malley
- Applicant: Cayman Chemical Company, Inc. , Myometrics, LLC
- Applicant Address: US MI Ann Arbor US CT New London
- Assignee: Cayman Chemical Company, Inc.,Myometrics, LLC
- Current Assignee: Cayman Chemical Company, Inc.,Myometrics, LLC
- Current Assignee Address: US MI Ann Arbor US CT New London
- Agency: Brinks Gilson & Lione
- Main IPC: C07D207/12
- IPC: C07D207/12 ; A61K31/4015 ; A61K31/4025 ; C07D207/273 ; C07D207/26 ; C07D409/06 ; A61L24/00 ; A61L24/02 ; A61L27/12 ; A61L27/36 ; A61L27/54 ; A61L27/58
Abstract:
Disclosed herein are compositions and methods of treating osteroporosis, bone fracture, bone loss, and increasing bone density by administration of compounds of formula (I) or compositions comprising a compound of formula (I) and a pharmaceutically acceptable carrier, wherein L1, L2, L4, R1, R4, R5, R6, and s are as defined in the specification.
Public/Granted literature
- US20160340306A1 DIFLUOROLACTAM COMPOSITIONS FOR EP4-MEDIATED OSTEO RELATED DISEASES AND CONDITIONS Public/Granted day:2016-11-24
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